diff --git a/programs/bpf_loader/src/lib.rs b/programs/bpf_loader/src/lib.rs
index 53890e3619..f0d453f38a 100644
--- a/programs/bpf_loader/src/lib.rs
+++ b/programs/bpf_loader/src/lib.rs
@@ -45,7 +45,7 @@ use {
             cap_accounts_data_len, disable_bpf_deprecated_load_instructions,
             disable_bpf_unresolved_symbols_at_runtime, disable_deprecated_loader,
             do_support_realloc, error_on_syscall_bpf_function_hash_collisions,
-            reduce_required_deploy_balance, requestable_heap_size,
+            reduce_required_deploy_balance, reject_callx_r10, requestable_heap_size,
         },
         instruction::{AccountMeta, InstructionError},
         keyed_account::keyed_account_at_index,
@@ -146,7 +146,9 @@ pub fn create_executor(
         syscall_bpf_function_hash_collision: invoke_context
             .feature_set
             .is_active(&error_on_syscall_bpf_function_hash_collisions::id()),
-        reject_callx_r10: false,
+        reject_callx_r10: invoke_context
+            .feature_set
+            .is_active(&reject_callx_r10::id()),
         // Warning, do not use `Config::default()` so that configuration here is explicit.
     };
     let mut create_executor_metrics = executor_metrics::CreateMetrics::default();
diff --git a/sdk/src/feature_set.rs b/sdk/src/feature_set.rs
index c51a1d2825..570e0dda9c 100644
--- a/sdk/src/feature_set.rs
+++ b/sdk/src/feature_set.rs
@@ -335,6 +335,10 @@ pub mod error_on_syscall_bpf_function_hash_collisions {
     solana_sdk::declare_id!("8199Q2gMD2kwgfopK5qqVWuDbegLgpuFUFHCcUJQDN8b");
 }
 
+pub mod reject_callx_r10 {
+    solana_sdk::declare_id!("3NKRSwpySNwD3TvP5pHnRmkAQRsdkXWRr1WaQh8p4PWX");
+}
+
 lazy_static! {
     /// Map of feature identifiers to user-visible description
     pub static ref FEATURE_NAMES: HashMap<Pubkey, &'static str> = [
@@ -413,6 +417,7 @@ lazy_static! {
         (stake_split_uses_rent_sysvar::id(), "stake split instruction uses rent sysvar"),
         (add_get_minimum_delegation_instruction_to_stake_program::id(), "add GetMinimumDelegation instruction to stake program"),
         (error_on_syscall_bpf_function_hash_collisions::id(), "error on bpf function hash collisions"),
+        (reject_callx_r10::id(), "Reject bpf callx r10 instructions"),
         /*************** ADD NEW FEATURES HERE ***************/
     ]
     .iter()