diff --git a/drift/lib/src/remote/protocol.dart b/drift/lib/src/remote/protocol.dart
index 76d17141..3ff69a1b 100644
--- a/drift/lib/src/remote/protocol.dart
+++ b/drift/lib/src/remote/protocol.dart
@@ -253,8 +253,8 @@ class DriftProtocol {
   }
 
   Object? _decodeDbValue(Object? wire) {
-    if (wire is List) {
-      return wire.cast<int>();
+    if (wire is List && wire is! Uint8List) {
+      return Uint8List.fromList(wire.cast());
     } else {
       return wire;
     }
diff --git a/drift/test/remote_test.dart b/drift/test/remote_test.dart
index 5fd9d36e..084c7a14 100644
--- a/drift/test/remote_test.dart
+++ b/drift/test/remote_test.dart
@@ -1,5 +1,7 @@
 import 'package:async/async.dart';
+import 'package:drift/drift.dart';
 import 'package:drift/remote.dart';
+import 'package:drift/src/remote/protocol.dart';
 import 'package:stream_channel/stream_channel.dart';
 import 'package:test/test.dart';
 
@@ -20,4 +22,27 @@ void main() {
 
     await shutdown(transformed);
   });
+
+  test('Uint8Lists are mapped from and to Uint8Lists', () async {
+    const protocol = DriftProtocol();
+
+    final request = Request(
+      1,
+      ExecuteQuery(StatementMethod.select, 'SELECT ?', [
+        Uint8List.fromList([1, 2, 3])
+      ]),
+    );
+
+    final mapped = protocol.deserialize(protocol.serialize(request)!);
+    expect(
+      mapped,
+      isA<Request>().having((e) => e.id, 'id', 1).having(
+            (e) => e.payload,
+            'payload',
+            isA<ExecuteQuery>()
+                .having((e) => e.method, 'method', StatementMethod.select)
+                .having((e) => e.args, 'args', [isA<Uint8List>()]),
+          ),
+    );
+  });
 }