diff --git a/os/hal/ports/STM32/STM32F4xx/hal_ext_lld_isr.c b/os/hal/ports/STM32/STM32F4xx/hal_ext_lld_isr.c
index b44374074..32c21cfaa 100644
--- a/os/hal/ports/STM32/STM32F4xx/hal_ext_lld_isr.c
+++ b/os/hal/ports/STM32/STM32F4xx/hal_ext_lld_isr.c
@@ -360,7 +360,9 @@ void ext_lld_exti_irq_enable(void) {
   nvicEnableVector(EXTI15_10_IRQn, STM32_EXT_EXTI10_15_IRQ_PRIORITY);
   nvicEnableVector(PVD_IRQn, STM32_EXT_EXTI16_IRQ_PRIORITY);
   nvicEnableVector(RTC_Alarm_IRQn, STM32_EXT_EXTI17_IRQ_PRIORITY);
+#if STM32_HAS_OTG1
   nvicEnableVector(OTG_FS_WKUP_IRQn, STM32_EXT_EXTI18_IRQ_PRIORITY);
+#endif
 #if STM32_HAS_ETH
   nvicEnableVector(ETH_WKUP_IRQn, STM32_EXT_EXTI19_IRQ_PRIORITY);
 #endif